NEW YORK — Older U.S. adults should roll up their sleeves for another COVID-19 shot, even if they got a booster in the fall, U.S. health officials said Wednesday.

The Centers for Disease Control and Prevention said Americans 65 and older should get another dose of the updated vaccine that became available in September — if at least four months has passed since their last shot. In making the recommendation, the agency endorsed guidance proposed by an expert advisory panel earlier in the day.

“Most COVID-19 deaths and hospitalizations last year were among people 65 years and older. An additional vaccine dose can provide added protection … for those at highest risk,” CDC Director Dr. Mandy Cohen said in a statement.

, especially to older people and those with underlying medical conditions. There are still more than 20,000 hospitalizations and more than 2,000 deaths each week due to the coronavirus, according to the CDC. And people 65 and older have the .

Some members of the advisory panel said a “should” recommendation is meant to more clearly prod doctors and pharmacists to offer the shots.

“Most people are coming in either wanting the vaccine or not,” said Dr. Jamie Loehr, a committee member and family doctor in Ithaca, New York. “I am trying to make it easier for providers to say, ‘Yes, we recommend this.’”

In September, the government recommended a new COVID-19 shot recipe built against a version of the coronavirus called XBB.1.5. That single-target vaccine replaced combination shots that had been targeting both the original coronavirus strain and a much earlier omicron version.