Liquid dietary supplements will usually include directions to refrigerate after opening, they usually have a brief shelf lifetime of 30 to 90 days sometimes (versus the 2 to a few years different complement varieties have).  

Whereas , others completely don’t. Some probiotics (like mindbodygreen’s ) are designed to be shelf-stable. And if that’s the case refrigerating them can mess with the standard, stability, and lively substances within the complement. 

And keep in mind, probiotics ship dwell microorganisms to assist colonize the intestine, so storing the complement incorrectly can (inadvertently) create an atmosphere that these organisms can’t survive in.    

“The dietary supplements that don’t explicitly state the necessity for refrigeration of their use or storage directions ought to by no means be refrigerated,” says Ferira. “It’s delightfully black and white.”